How to optimize Bohr effect.
Normally we presume that oxygen is important as we inhale it and carbon dioxide is useless, but this fact may surprise you that carbon dioxide is more important for controlling the urge to breathe, while oxygen is essential for metabolic survival. The body monitors carbon dioxide levels to regulate the breathing rate and maintain blood pH between (7.35 to 7.45) levels, making carbon dioxide primary driver of ventilation, whereas oxygen levels must drop to function as an emergency stimulus. Now the question is why carbon dioxide is more important for respiratory drive. The brain triggers the urge to breath primary when carbon dioxide levels rise, but not due to drop in oxygen levels. Carbon dioxide acts as buffer to maintain proper acid-base balance in the blood. Excess carbon dioxide makes blood acidic, demanding immediate removal of carbon dioxide. While carbon dioxide is the normal driver, low oxygen levels (hypoxia) will eventually trigger rapid breathing, though this is a s...